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NEUROSCIENCE – 2022

Questions from the 2022 Neuroscience Module + Annuals

Fine touch is carried by the dorsal column, while crude touch is carried by the anterior spinothalamic tract—which one is affected here?

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Category: NeuroSciences – Anatomy

A patient loses the sensation of crude touch, while the sensation of fine touch is intact. Which of the following tracts is most likely to be damaged?

Consider which brain wave pattern is dominant when someone is actively thinking and engaging in a task.

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Category: Neurosciences – Physiology

Which of the following waves are seen when a person is awake and is alert?

Think about which cells in the substantia nigra are primarily affected in Parkinson’s disease and what neurotransmitter they produce.

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Category: Neurosciences – Pathology

Which of the following happens in Parkinson’s disease?

Consider which cranial nerve exits through the stylomastoid foramen and what functions it controls.

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Category: NeuroSciences – Anatomy

An 80-year-old male came to the hospital with a head injury due to a bad fall. He had a stylomastoid fracture. Which of the following nerves is most likely to be damaged?

Think about which glial cells have an immune function—these do not arise from the same germ layer as neurons.

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Category: Neurosciences – Embryology

Which of the following glial cells is not derived from the neuroectoderm?

This part of the brain looks white because it’s packed with myelinated nerve fibers, helping signals travel fast.

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Category: Neurosciences – Histology

Which of the following cell structures constitute the white matter of the central nervous system?

Think about chronic infections that cause fibrin deposition in the CSF, rather than acute inflammatory responses.

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Category: Neurosciences – Pathology

What does a ‘cobweb’ appearance of the CSF indicate?

A teenager with chronic headaches and seizures, and a brain mass with past and recent bleeds—think of a hidden ticking time bomb in the brain’s blood supply.

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Category: Neurosciences – Pathology

A 15-year-old girl presented to the outpatient department with complaints of headaches for the past 8 months. Over a 2-week period, she has a generalized seizure. On physical examination, there is no papilledema or movement disorder. Computed tomography (CT) scan of the head shows a 2 cm mass in the right frontal lobe and shows evidence of recent and remote hemorrhage. What is the most likely diagnosis?

Imagine suddenly falling asleep in the middle of a conversation or collapsing when laughing—which disorder fits this?

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Category: Neurosciences – Physiology

Which of the following disorders is characterized by excessive daytime sleepiness and sudden loss of muscle tone?

These fibers are responsible for sensing muscle tension and help prevent muscle injury from overexertion. What type of sensory afferent would handle this task?

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Category: Neurosciences – Physiology

Which of the following types of nerve fibers innervate Golgi tendon organs?

Think of the that nucleus as the “feeding center”—damage leads to starvation and weight loss.

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Category: NeuroSciences – Anatomy

A 20-year-old girl presented with severe weight loss. On history, she admitted that her appetite is greatly reduced and she is experiencing sleep disturbances for the last two months. Which hypothalamic nucleus controls the appetite center?

Think about the embryonic structure responsible for sensory processing in the spinal cord.

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Category: Neurosciences – Embryology

The posterior grey horn of the spinal cord develops from which of the following?

The sympathetic system prepares the body for “fight or flight”

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Category: Neurosciences – Physiology

Which of the following functions is the result of an increased activity of the sympathetic nervous system?

Think of vasculitis cutting off blood supply to different nerves at different sites, leading to patchy, asymmetric nerve involvement.

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Category: Neurosciences – Pathology

Peripheral nerves are often damaged in many different forms of different vasculitis including polyarteritis nodosa (PAN), Churg-Strauss syndrome, and Wegener’s granulomatosis. Which of the following is the most common clinical picture in these disorders?

Think of the dopamine-producing structure in the midbrain that degenerates in Parkinson’s disease.

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Category: Neurosciences – Pathology

Damage to which structure causes Parkinson’s disease?

Think about non-fluent aphasia, where patients understand language but struggle to form words.

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Category: NeuroSciences – Anatomy

A 45-year-old female is in recovery from a stroke. She is found to have difficulty in speech. She can write the words and can understand their meanings but is unable to produce words. Where is the cerebral cortical area responsible for the above-stated condition located?

Think of the brain structure essential for memory formation—damage leads to anterograde amnesia.

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Category: NeuroSciences – Anatomy

During the removal of a brain tumor in a patient, a part of the brain was removed. Upon successful awakening, the patient is unable to form new memories. However, he can recall most previously learned memories satisfactorily. Which of the brain area may have been affected during the operation?

 Think about the type of prevention that focuses on stopping a disease from occurring in the first place. This strategy involves lifestyle changes and healthy habits to reduce the risk of developing conditions like hypertension and stroke. Which level of prevention aligns with this approach?

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Category: Neurosciences – Community Medicine + Behavioural Sciences

Practicing a healthy lifestyle by eating a diet rich in fruits and vegetables, and maintaining a healthy weight for the prevention of hypertension and stroke is advised by physicians. Which one of the following preventions is applied here?

Look for a fiber that connects different parts within the same hemisphere, rather than crossing to the other hemisphere or linking to lower brain structures.

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Category: NeuroSciences – Anatomy

Association fibers are the nerve fibers that connect different regions within the same hemisphere. Which of the following is categorized as the association fiber?

Think about how the brain filters out background noise or repetitive stimuli to focus on important information

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Category: Neurosciences – Physiology

Which one of the following is the capability of the brain to ignore unimportant information?

If a patient ignores one side of their body but has no paralysis, think about right parietal lobe damage

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Category: NeuroSciences – Anatomy

A 55-year-old male patient presents to the neurology clinic with the complaint of not being able to acknowledge the left side of his body. He does not wash, shave, or use the left side of his body. A lesion in which of the following areas of the cerebral cortex is the most likely cause for this deficit in the patient?

Once paralysis has set in, prevention is no longer an option—what’s the next best step to help the child function better?

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Category: Neurosciences – Community Medicine + Behavioural Sciences

Which of the following is the most appropriate intervention after a child has been diagnosed with paralytic poliomyelitis?

This nerve lets you shrug your shoulders and turn your head—without it, even a simple “no” shake becomes difficult.

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Category: NeuroSciences – Anatomy

A 67-year-old male patient presents to the clinic with complaints of not being able to shrug his shoulders and move his head from side to side over the last few days. Which of the following nerves is most likely to be damaged in this case?

Think about the limbic structure that curves downward in front of the interventricular foramen.

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Category: NeuroSciences – Anatomy

Which of the following is present anterior to the interventricular foramen?

Think about the spinocerebellar pathways—the cuneocerebellar tract is specifically for the upper body, just like the dorsal spinocerebellar tract is for the lower body.

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Category: NeuroSciences – Anatomy

The cuneocerebellar pathway conveys information from which of the following?

a synaptic messenger with specific receptors and pharmacological modulation (agonists/antagonists).

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Category: Neurosciences – Physiology

A compound that is synthesized in a neuron, has a receptor in vicinity, and has agonists and antagonists defines which of the following terms?

Think about which nerve controls facial expressions and runs alongside the auditory nerve

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Category: NeuroSciences – Anatomy

Which nerve exits the skull from the internal acoustic meatus along with the vestibulocochlear nerve (CN VIII)?

Think about how water appears in T2-weighted MRI—structures with high water content show up as hyperintense

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Category: Neuroscience – Radiology

In a T2WI section magnetic resonance imaging (MRI), the cerebrospinal fluid appears as which of the following?

This cerebellar region talks to the motor cortex to plan movements before they happen, ensuring smooth execution.

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Category: NeuroSciences – Anatomy

Which of the following parts of the cerebellum is involved in planning and coordinating movements?

Think of lateral medullary syndrome (Wallenberg syndrome), which is caused by an infarct in PICA, affecting the medulla.

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Category: NeuroSciences – Anatomy

Which one of the following arteries supplies the medulla oblongata?

Think about neurotransmitters that naturally relieve pain

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Category: Neurosciences – Biochemistry

To which of the following classes do the endorphins belong?

This natural anticoagulant inhibits thrombin and is supercharged by heparin to prevent clotting.

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Category: Neurosciences – Pharmacology

Heparin binds to which of the following molecules to produce its anti-coagulant effect?

Damage to this compact white matter structure leads to contralateral weakness with increased reflexes and tone—what kind of paralysis does that indicate?

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Category: Neurosciences – Pathology

A 65-year-old male suffers from a cerebrovascular accident. An MRI scan reveals a lesion in the left internal capsule. Which of the following signs or symptoms is most likely to be observed in this patient?

Think of the hypothalamic nucleus that controls sleep-wake cycles by regulating melatonin secretion.

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Category: NeuroSciences – Anatomy

Which of the following hypothalamic nuclei acts as the body’s primary circadian pacemaker?

Think of the forebrain vesicle (telencephalon) that also forms the cerebral cortex, where the basal nuclei reside.

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Category: Neurosciences – Embryology

Basal nuclei are a collection of cell bodies that control voluntary movements. Which of the following vesicles gives rise to basal nuclei?

Think of the ciliated cells that help circulate CSF in the ventricles and spinal cord.

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Category: NeuroSciences – Anatomy

Which of the following cells line the central canal?

The genu of the internal capsule carries motor fibers to cranial nerves, which are crucial for speech articulation.

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Category: NeuroSciences – Anatomy

Which of the following can be caused by an infarction of the genu of the internal capsule?

This ATP-powered transporter keeps many drugs and toxins out of the brain, making it a major challenge for CNS drug delivery.

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Category: Neurosciences – Biochemistry

Which of the following is an active efflux transporter in the blood-brain barrier?

Focus on the neurotransmitter that is not a catecholamine and is instead linked to mood regulation and sleep.

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Category: Neurosciences – Biochemistry

Which of the following is not derived from tyrosine?

Before reaching the brain, visual information travels in a way that initially keeps things separate but later mixes signals from both sides. Where in this pathway does this crucial switch happen?

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Category: NeuroSciences – Anatomy

Which of the following statements distinguishes the optic nerve from the optic tract?

This brain region helps convert sounds into meaningful words—without it, speech sounds like meaningless noise.

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Category: NeuroSciences – Anatomy

A 56-year-old woman presents to the outpatient clinic with the complaint of not being able to understand spoken language. She can, however, interpret written symbols and speech. Which of the following areas of the cerebral cortex is most likely to be damaged in this case?

A wild, flinging movement on one side of the body points to damage in a small but crucial part of the basal ganglia circuit—what structure normally suppresses such movements?

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Category: NeuroSciences – Anatomy

A 35-year-old man is brought to the emergency room after he suffers a head injury in a road traffic accident. It is observed that he has flailing movement in his left upper limb. Which of the following structures is the most likely site of lesion in this case?

Think about the three-layered structure of the cerebellar cortex and the types of inhibitory interneurons present in each layer.

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Category: NeuroSciences – Anatomy

Which of the following is the correct option regarding the cerebellum?

Think of REM sleep’s role—without it, cognitive function declines.

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Category: Neurosciences – Physiology

Prolonged rapid eye movement (REM) sleep deprivation can result in which of the following?

Think about the jugular foramen, which transmits CN IX, X, and XI—it is located in the posterior cranial fossa, primarily formed by the occipital bone.

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Category: NeuroSciences – Anatomy

A radiologist, while reading the computed tomography scan, noticed a jugular tubercle grooved by IX, X, and XI cranial nerves. This tubercle is part of which of the following bones?

Think of the hypothalamic nucleus that, when stimulated, drives a person to eat and drink.

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Category: Neurosciences – Physiology

Which nucleus of the hypothalamus is involved in the regulation of thirst and hunger?

Think about a condition where neurons fire excessively due to reduced inhibition—leading to uncontrolled electrical activity in the brain.

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Category: Neurosciences – Community Medicine + Behavioural Sciences

Which of the following conditions is associated with low levels of gamma-aminobutyric acid (GABA)?

Think about how nerve impulse transmission is stopped..

so think about this.. What prevents action potential propagation.

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Category: Neurosciences – Physiology

During suturing of a wound, a patient receives local anesthesia around the wound area. After this, he did not feel any needle pain during suturing. Which of the following option could be the reason for this?

Fluent but meaningless speech, poor comprehension, and lack of awareness = Wernicke’s aphasia.

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Category: NeuroSciences – Anatomy

Destructive lesion of the Wernicke’s area results in which of the following?

CN III compression → “Blown pupil” (mydriasis) + impaired eye movement.

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Category: Neurosciences – Pathology

A 39-year-old woman has had a severe headache for 3 days. On physical examination, she is afebrile and normotensive. Fundoscopic examination shows papilledema on the right. One day later, she has right pupillary dilation and impaired ocular movement. Which of the following lesions best explains these findings?

Doctors must communicate in a way which avoids misleading patients into unnecessary treatments.

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Category: Neurosciences – Community Medicine + Behavioural Sciences

A surgeon working in a private rehabilitation facility encounters a patient with a certain tumor that responds only to radiotherapy and surgery. The surgeon is enthusiastic to perform the surgery and proceeds to convince the patient to perform the surgery despite the lack of evidence of surgery being the better option. Which of the following principles of ethical communication has the surgeon breached in the above scenario?

Think about how venous blood from the superior part of the brain ultimately reaches the internal jugular vein.

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Category: NeuroSciences – Anatomy

Where does the superior sagittal sinus drain into?

When a patient is completely unresponsive, someone has to step in and take control of the decisions—but who gets that power, and on what basis?

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Category: Neurosciences – Community Medicine + Behavioural Sciences

An 85-year-old male is in a coma in a hospital. His daughter makes all the decisions regarding his treatment on his behalf. Which of the following options best describes the type of consent in this scenario?

Think about the essential amino acid that serves as a precursor for a neurotransmitter involved in mood regulation.

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Category: Neurosciences – Biochemistry

Serotonin or 5-hydroxytryptamine is synthesized from which of the following?

When someone overdoses on opioids, this drug kicks opioids off their receptors and brings them back to life.

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Category: Neurosciences – Pharmacology


Which of the following is an opioid receptor antagonist used as a drug for opioid overdose and toxicity?

A person with damage to this area knows what they want to say but struggles to say it. What part of the brain controls the formation of speech?

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Category: NeuroSciences – Anatomy

A 42-year-old woman suffered a head injury in a road traffic accident. She was brought to the emergency room and underwent an MRI scan, which revealed a hemorrhage in the inferior frontal gyrus. Which of the following symptoms is the most likely manifestation of a lesion in this area of the cerebral cortex?

This cranial nerve is responsible for moving the eye and also controls pupil size and lens focusing—which one is it?

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Category: Neurosciences – Physiology

The craniosacral outflow constitutes the parasympathetic nervous system. The parasympathetic fibers of which of the following nerves control the pupillary and accommodation reflexes?

Think of small penetrating arteries that supply the deep structures of the brain—the lenticulostriate arteries are key.

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Category: NeuroSciences – Anatomy

Which of the following arteries supply the corpus striatum and internal capsule?

Think of opioid overdose symptoms

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Category: Neurosciences – Pharmacology

Which of the following statements is correct regarding the mu receptor stimulation?

The CSF is being produced but cannot flow past a blocked passageway—which narrow channel in the brain is most likely affected?

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Category: Neurosciences – Pathology

A child suffers from non-communicating hydrocephalus. Which of the following is a characteristic of non-communicating hydrocephalus?

Think about the brain region involved in decision-making, attention, and short-term cognitive tasks

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Category: Neurosciences – Physiology

Maintaining working memory contents for a dozen seconds requires which of the following?

Think about the enzyme that creates acetylcholine from choline and acetyl-CoA

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Category: Neurosciences – Biochemistry

Which of the following is the rate-limiting enzyme of acetylcholine synthesis?

Think about unconscious, rule-based learning that occurs effortlessly in childhood..

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Category: Neurosciences – Community Medicine + Behavioural Sciences

Young children can immediately repeat short sentences spoken by their parents and siblings, and also produce new sentences that follow the rules of their native language. The ability to produce new, rule-governed sentences is thought to involve which kind of learning?

Gray rami communicantes carry postganglionic sympathetic fibers from the sympathetic chain to spinal nerves.

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Category: NeuroSciences – Anatomy

Gray rami communicans are derived from which of the following?

This toxin is actively secreted by Corynebacterium diphtheriae and inhibits protein synthesis, leading to cell death and tissue damage.

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Category: Neurosciences – Pathology

Which of the following terms correctly describes the diphtheria toxin?

It messes with vitamin K → Fix it with more vitamin K!

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Category: Neurosciences – Pharmacology

Vitamin K reverses the overdose of which of the following agents?

You can’t change your genes, gender, or age, but you can change your weight and lifestyle.

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Category: Neurosciences – Community Medicine + Behavioural Sciences

Which of the following is a modifiable risk factor for stroke?

Think about fluent aphasia —speech is fluent but nonsensical, and comprehension is impaired.

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Category: Neurosciences – Physiology

A patient presents with the inability to interpret thoughts, although he is capable of expressing individual words or even short phrases. Which area of the brain is most likely to be affected?

This opioid drug helps stop excessive bowel movements but doesn’t get you high—what is it?

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Category: Neurosciences – Pharmacology

Which of the following opioid drugs is used to treat diarrhea?

The patient understands speech but struggles to speak—which part of the brain controls speech production?.. Can’t believe i would have to repeat hints, but hey… I am as washed up as this question bank 😮

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Category: NeuroSciences – Anatomy

A 45-year-old woman suffers from a stroke and has difficulty with speech. She can write and understand speech but is unable to produce any words. The area affected in this case is located in which of the following gyri of the cerebral cortex?

If a patient has meningitis symptoms + TB history + MRI findings suggesting TB, What’s the treatment???—waiting can be fatal!

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Category: Neurosciences – Pathology

A 35-year-old housewife presents to the neurology clinic for evaluation of persistent headache and vomiting for one week with intermittent clouding of consciousness and confusion. She had a prior history of weight loss and fever for the past two months. Two years back, she was treated for pulmonary tuberculosis and became asymptomatic. On examination, signs of meningeal irritation are positive with bilateral papilledema. MRI brain contrast suggests central nervous system tuberculosis. Cerebrospinal fluid detailed report is awaited. What is the most appropriate next step in the management of this patient?

Think about what structures are herniating—if only meninges and CSF are involved..

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Category: Neurosciences – Embryology

Cystic mass containing meninges with CSF only protrudes at the thoracolumbar region of a newborn. This cystic mass would be classified as which of the following defects?

Think of the autonomic system that promotes digestion, relaxation, and energy conservation

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Category: Neurosciences – Physiology

During resting, the heart rate is slowed, pupils are constricted, peristalsis and glandular activity are increased, sphincters are opened, and the bladder wall is contracted. Which of the following system is activated in this state?

This thin dural membrane covers the pituitary gland and prevents direct contact with the optic chiasm, allowing the pituitary stalk to pass through it.

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Category: NeuroSciences – Anatomy

While operating on the pituitary gland, a surgeon tries to secure the optic chiasma. Which of the following structures separates the pituitary gland from the optic chiasm?

Think about the catecholamine pathway and the neurotransmitter that is synthesized early in this process.

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Category: Neurosciences – Biochemistry

What is the biologically active amine form of phenylalanine?

Think about the ion that enters through NMDA receptors and is required for synaptic strengthening

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Category: Neurosciences – Physiology

Long-term potentiation is identified in hippocampal mossy fibers by an increase in which of the following ions in the postsynaptic area?

Great ideas don’t just appear instantly—they require gathering knowledge, subconscious thinking, breakthrough moments, evaluation, and application.

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Category: Neurosciences – Community Medicine + Behavioural Sciences

As a medical professional, you have to come up with ideas for research that are original, unique, new, and relevant to your field of practice. This involves creative thinking. Which of the following will you follow?

Which neurotransmitter is released in a fight-or-flight response and affects both vasoconstriction and heart rate?

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Category: Neurosciences – Physiology

Which of the following neurotransmitters equally excites both alpha and beta-adrenergic receptors?

This brainstem region is a natural painkiller hub—when damaged, pain perception increases due to loss of inhibition.

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Category: NeuroSciences – Anatomy

A 55-year-old woman presents to the emergency room with a head injury following a road traffic accident. MRI scans reveal damage to the periaqueductal gray area of the midbrain. A lesion in this area is most likely to result in which of the following signs or symptoms?

Think of the midbrain nucleus that influences voluntary movements, particularly of the upper limb flexors—this is the red nucleus, which gives rise to the rubrospinal tract.

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Category: NeuroSciences – Anatomy

A 55-year-old male presents to the emergency department after a road traffic accident. Magnetic resonance imaging (MRI) shows damage to the corticospinal tract on one side. Which of the following tract serves as an “alternative pathway” for transmitting motor signals to the spinal cord?

Think about the receptor type found at all autonomic ganglia, whether sympathetic or parasympathetic

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Category: Neurosciences – Physiology

Which type of cholinergic receptor is found at synapses between preganglionic and postganglionic neurons of the sympathetic system?

lack the protective myelin sheath, allowing anesthetic agents to more easily block sodium channels and inhibit nerve conduction.

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Category: Neurosciences – Physiology

Which of the following nerve fiber types is most sensitive to anesthetic agents?

A posterior cerebral artery (PCA) infarct affecting the primary visual cortex

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Category: NeuroSciences – Anatomy

A vascular lesion of the primary visual area (Brodmann area 17) may cause which one of the following defects?

Think about which pathway transmits crude touch rather than fine, discriminatory touch

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Category: NeuroSciences – Anatomy

During an examination of a young boy, the child feels very ticklish so it becomes difficult for the doctor to examine him. Which of the following tract carries the above sensation?

Which motor neuron type actually makes muscles contract?

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Category: Neurosciences – Physiology

Which of the following types of neurons innervate extrafusal muscle fibers?

“gold standard” – Think of the vice city cheatcode. ***** _ _ _ _ _ _

The Second One.

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Category: Neuroscience – Radiology

What is the major advantage of magnetic resonance imaging (MRI) over computed tomography (CT) scan?

When the main bridge between brain hemispheres is missing, fluid-filled spaces expand, creating an abnormally enlarged and spaced ventricle appearance on imaging.

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Category: Neurosciences – Embryology

A child is born with agenesis of the corpus callosum which is a major commissural fiber. Which of the following findings is most likely to be seen in radiological scans of this child’s brain?

Think about what type of sensations are carried by the dorsal column and how their loss might affect body coordination.

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Category: Neurosciences – Physiology

Lesion of the dorsal column results in which of the following?

A clear sensory level + UMN signs + autonomic dysfunction?

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Category: NeuroSciences – Anatomy

A 20-year-old male presented to the neurology outpatient department with complaints of bilateral lower limb weakness and urinary incontinence for the last 4 days. On examination, he had decreased power in both lower limbs with increased tone, brisk reflex, and upgoing plantar. The sensory level was found at the xiphisternum. What is the most likely neurological localization in this case?

Think about which ion is most responsible for depolarizing the postsynaptic neuron in neuromuscular junctions and autonomic ganglia.

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Category: Neurosciences – Physiology

Acetylcholine increases the permeability of which of the following ions when it binds to nicotinic receptors at the postsynaptic neuron?

This white matter tract allows you to repeat what you hear—damage to it results in conduction aphasia.

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Category: NeuroSciences – Anatomy

Which of the following structures connects Wernicke’s area to Broca’s area?

This theory suggests that bodily reactions dictate emotions—you don’t cry because you’re sad; you feel sad because you cry.

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Category: Neurosciences – Community Medicine + Behavioural Sciences

Ali saw a snake and he started trembling. The statement that Ali is afraid because he trembled is better explained by which of the following theories?

Sweat glands are a unique exception in the sympathetic system

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Category: Neurosciences – Physiology

The sweat glands and piloerector muscles of hairy skin are innervated by which of the following fiber types?

  • VPL = Body
  • VPM = Face 

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Category: NeuroSciences – Anatomy

Which of the following sensations are relayed at the ventral posterolateral nuclei of the thalamus before reaching the post-central gyrus?

Consider conditions that affect the neuromuscular junction and how autoimmune processes could interfere with signal transmission.

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Category: Neurosciences – Pathology

Which of the following is an autoimmune disease affecting the nicotinic acetylcholine receptors?

Think about neural tube defects—the anterior neuropore is responsible for forming the brain, while the posterior neuropore forms the spinal cord.

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Category: Neurosciences – Embryology

Meroanencephaly is defined as the partial absence of the brain. It is caused by which of the following defects?

In Parkinson’s, the resting tremor appears on one side, but the damage is on the opposite side of the brain. What part of the brain degenerates in PD?

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Category: NeuroSciences – Anatomy

A 55-year-old man with a history of resting tremors in his right hand dies in a road traffic accident and undergoes an autopsy. His neurological examination is likely to reveal degeneration of neurons in which of the following structures?

Think of olfactory signals crossing between hemispheres

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Category: NeuroSciences – Anatomy

What are the commissural fibers associated with the olfactory pathway called?

This nervous system is responsible for the “fight or flight” response and has a chain of ganglia running along the spine.

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Category: Neurosciences – Physiology

Which part of the nervous system consists of two ganglionated nerve trunks extending the entire length of the vertebral column on both sides?

Consider the supportive glial cells that help regulate the brain’s microenvironment and contribute to the selective permeability of the BBB.

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Category: Neurosciences – Physiology

Which one of the following forms the blood-brain barrier?

distinguishes between sensory ataxia (dorsal column damage) and cerebellar ataxia—only sensory ataxia improves with visual input.

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Category: NeuroSciences – Anatomy

A lesion in the dorsal column tract causes loss of proprioception resulting in severe ataxia. It can be confirmed by which of the following signs?

A post-infectious, ascending, flaccid paralysis with areflexia? Think Guillain-Barré syndrome 

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Category: Neuroscience – Radiology

A 25-year-old male is brought to the emergency department with complaints of all four limbs weakness for 3 days with a history of diarrhea 3 weeks before. On examination, he has flaccid areflexic quadriparesis and the sensations are intact with downgoing plantar. What should be the diagnostic investigation in this case?

Think about the pathway responsible for fine touch, vibration, and proprioception.

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Category: NeuroSciences – Anatomy

Which of the following tract conveys information about highly localized touch sensations and proprioception?

Think of the basal ganglia structure that controls movement inhibition and how its damage leads to uncontrolled flinging movements.

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Category: NeuroSciences – Anatomy

Hemiballismus is caused due to damage to which of the following structures?

A strong magnet + an electronic device inside the body = serious trouble.

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Category: Neuroscience – Radiology

What is the absolute contraindication of magnetic resonance imaging (MRI)?

Think about the hypothalamic center responsible for stopping food intake—its damage results in uncontrolled eating and weight gain.

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Category: NeuroSciences – Anatomy

A lesion in which of the following nuclei in the hypothalamus causes hypothalamic obesity?

Think of the biological clock (SCN) that controls the light-dark cycle and melatonin release.

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Category: NeuroSciences – Anatomy

Secretion of melatonin by the pineal gland is regulated by which one of the following parts of the diencephalon?

Consider psychiatric disorders where dopamine-blocking drugs (antipsychotics) are the main treatment.

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Category: Neurosciences – Pathology

Which of the following is associated with increased dopamine levels?

Think of the fourth ventricle lying between the brainstem and cerebellum

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Category: NeuroSciences – Anatomy

A child is brought to the emergency room with complaints of severe vomiting and seizures. A radiologic scan revealed dilation of the fourth ventricle. Which of the following structures form(s) the floor of the fourth ventricle?

This area helps you speak fluently, but if damaged, you struggle to form words despite understanding speech.

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Category: NeuroSciences – Anatomy

Which of the following Brodmann’s areas corresponds to the motor speech area of Broca?

A “crossed pattern” of motor deficits (one side of the face, opposite side of the body) often means a brainstem lesion—where does the hypoglossal nerve originate?

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Category: NeuroSciences – Anatomy

A 55-year-old man presents to the neurology clinic with the complaint of right-sided weakness of the body and left-sided weakness of the face with the tongue deviating to the left upon protrusion. Which of the following structures is most likely to be affected in this case?

Think about deep sleep disorders that all occur during Stage 3 SWS.

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Category: Neurosciences – Physiology

Which of the following is mostly associated with slow-wave sleep?

preventing the use of long-chain fatty acids as an energy source.

 

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Category: Neurosciences – Biochemistry

What is the reason that brain tissue cannot utilize fatty acids for energy?

The brain needs nutrients but must also be protected from toxins, infections, and fluctuations in blood chemistry—what structure manages this balance?

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Category: Neurosciences – Biochemistry

Which of the following statements correctly describes the main function of the blood-brain barrier?

Think about the midbrain structure responsible for auditory reflexes and signal integration.

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Category: NeuroSciences – Anatomy

Auditory fibers run in the lateral lemniscus terminate in which of the following structures?

Cerebellar lesions cause ipsilateral limb ataxia—look at which side the coordination is impaired.

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Category: NeuroSciences – Anatomy

A 60-year-old hypertensive male was taken to the emergency department with complaints of sudden onset of nausea and vomiting. The examination revealed slurred speech and dysmetria on finger-to-nose test on the left side. However, his gait was normal. In which of the following areas lesion has occurred?

Initially, the reflexes might be sluggish or absent, but over time, they may become overactive due to the disruption of higher brain control.

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Category: NeuroSciences – Anatomy

In complete cord transection at the cervical level, what would be observed on checking for reflexes of the limbs?

Think about the thalamic relay station for sensory information coming from the face and trigeminal nerve.

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Category: NeuroSciences – Anatomy

Which of the following thalamic nuclei receives sensory afferents from the face and mouth?

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